PFAS暴露透過攻擊耳蝸毛細胞與螺旋神經節神經元引起聽力損失

// PFAS exposure induces hearing loss by targeting cochlear hair cells and spiral ganglion neurons

本研究探討五種PFAS化合物混合物經飲水暴露七週對小鼠聽力的影響｜結果顯示聽力閾值提升，外毛細胞功能受損，並伴隨耳蝸毛細胞及螺旋神經節神經元減少｜證實PFAS暴露會損傷耳蝸感覺與神經結構，導致高頻聽力損失，提供PFAS致耳毒性的新證據。

// This study investigated hearing loss caused by PFAS exposure in mice, using a mixture of five PFAS compounds in drinking water for seven weeks. Hearing tests showed increased thresholds and impaired outer hair cell function, alongside a loss of cochlear hair cells and spiral ganglion neurons. The results demonstrate that PFAS exposure leads to high-frequency hearing loss by damaging both sensory and neural components of the cochlea. This provides new evidence of PFAS-induced ototoxicity affecting auditory function.

Published 2026年5月21日