哺乳動物內耳中的礦物皮質激素受體與糖皮質激素受體：範疇綜述

// Mineralocorticoid and glucocorticoid receptors in the mammalian inner ear: a scoping review

本研究回顧哺乳類內耳中礦物皮質素受體（MR）與糖皮質素受體（GR）的分布｜分析23項研究發現兩者廣泛存在於耳蝸與前庭區域，但人類MR數據有限｜結果顯示受體分布具物種與發育階段差異，對立體模型選擇和類固醇治療研究具指導意義。

// This study reviewed the distribution of mineralocorticoid (MR) and glucocorticoid (GR) receptors in the mammalian inner ear to understand their roles in stress, inflammation, and corticosteroid treatment outcomes. They analyzed 23 studies showing both receptors are widely present in cochlear and vestibular regions but noted limited human data, especially for MR. Variations across species, developmental stages, and study methods challenge direct comparisons. The findings highlight an incomplete but broadly conserved receptor map, influencing model selection and interpretation in steroid research for hearing and balance.

Published 2026年5月26日