鳥類時差（ITD）迴路的抑制性輸入

// Inhibitory inputs to avian ITD circuits

本研究探討鳥類上橄欖核（SON）對層狀核（NL）抑制輸入的作用｜利用病毒標記與GABA、甘氨酸受體阻斷劑，揭示SON對NL神經元的抑制機制｜發現SON的抑制提高NL對雙耳時間差（ITD）的動態調節範圍，且有助維持ITD敏感性，強化聲音定位能力。

// This study investigates the role of inhibitory input from the Superior Olivary Nucleus (SON) to the nucleus laminaris (NL) in birds, which processes interaural time differences (ITDs) for sound localization. Using viral tracers and pharmacological blockers of GABA and glycine receptors in vivo, the researchers characterized SON projections and inhibitory effects on NL neurons. They found that inhibition from SON enhances the dynamic range of ITD tuning in NL without shifting best ITD, with distinct inhibitory responses following sound onset and offset. These findings support that GABAergic and glycinergic inhibition from SON helps NL neurons maintain ITD sensitivity across sound levels.

Published 2026年5月31日