// Management of pediatric sialorrhea: A systematic review with a stepwise evidence-based clinical algorithm
本研究系統回顧22篇包含1028名兒童的流口水治療，涵蓋行為療法、藥物、肉毒桿菌素與手術方法｜行為療法短期見效有限，抗膽鹼藥物中期有效但副作用明顯，肉毒桿菌素可逆且適用短中期，手術則適用重度病例且效果持久｜提出依嚴重度和多學科評估的分階段治療策略，強調早期保守治療，建議未來進行前瞻性驗證。
// This study systematically reviewed treatments for pediatric sialorrhea, including behavioral, pharmacologic, botulinum toxin, and surgical approaches, across 22 studies with 1028 children. Behavioral therapies showed modest short-term benefits, anticholinergic drugs had moderate medium-term efficacy but notable side effects, botulinum toxin offered reversible short-to-medium term reductions, and surgery provided the most durable results for severe cases. The authors developed a practical, stepwise management algorithm based on severity and multidisciplinary input, emphasizing early conservative treatment and reserving invasive options for refractory cases. Prospective validation of this approach is recommended.
Published 2026年6月4日
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