耳蝸去傳入損傷影響暴露於凱納酸鹽之虎皮鸚鵡的聲音起始線索感知

// Cochlear deafferentation impairs perception of acoustic onset cues in kainate-exposed budgerigars

本研究探討興奮毒性引起的耳蝸突觸病變，如何影響鸚鵡對噪音中音調的辨識能力｜使用耳蝸內注射賜安酸（kainic acid）誘發突觸病變，發現鸚鵡能正常辨識長音，但在短音與噪音同時出現時偵測能力下降｜結果顯示耳蝸突觸病變會選擇性損害聲音起始訊號的感知，可能解釋人類在嘈雜環境中語言理解困難的原因。

// This study investigated how cochlear synaptopathy, induced by excitotoxicity, affects tone-in-noise detection in trained budgerigars. Using intracochlear kainic-acid to cause synaptopathy, the researchers found that animals detected long tones normally but showed impaired detection of short tones presented simultaneously with noise onset. The findings suggest cochlear synaptopathy selectively disrupts perception of acoustic onset cues. This impairment could underlie difficulties in speech perception in noisy environments for humans with synaptopathy.

Published 2026年6月5日