長期中度噪音暴露後耳蝸核的頻率特異性與水準依賴性改變

// Frequency-specific and level-dependent alteration in cochlear nucleus following prolonged moderate noise exposure

本研究探討小鼠暴露於65分貝中等噪音1小時後，對耳蝸核（負責初級聽覺處理）影響｜發現聲頻特定變化：暴露頻率及其以上呈抑制，低頻則活動增加｜6小時內部分恢復，豐富聲音環境有助加速聽覺中樞功能重組與復原。

// This study examined how 1-hour exposure to moderate noise (65 dB SPL) affects the cochlear nucleus (CN) in mice. Extracellular recordings showed frequency-specific changes: suppression at the exposure and higher frequencies, and increased activity at lower neighboring frequencies. These changes partially recovered within 6 hours, especially when mice were in an enriched acoustic environment. The results indicate rapid CN reorganization after moderate noise exposure influenced by both peripheral input and CN circuitry, with recovery aided by acoustic enrichment.

Published 2026年6月10日