// Medical Therapy for NF2-related Schwannomatosis: A Systematic Review of Current Evidence
本系統性回顧評估NF2相關聽神經鞘瘤的醫療治療,重點在於腫瘤控制與聽力改善|貝伐單抗(Bevacizumab)效果最佳,提升最多61%患者聽力,並使腫瘤縮小達60%|其他如mTOR抑制劑、酪氨酸激酶抑制劑及VEGFR疫苗效果不一,需更多隨機試驗驗證療效與持久性。
// This systematic review evaluated medical treatments for NF2-related vestibular schwannomas, focusing on tumor control and hearing outcomes. Bevacizumab showed the most consistent benefits, improving hearing in up to 61% of patients and reducing tumor size in up to 60%. Other therapies like mTOR inhibitors, tyrosine kinase inhibitors, and VEGFR vaccines had variable and less consistent results. The study highlights the need for high-quality randomized trials to better assess these treatments' efficacy and durability.
Published 2026年6月11日
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