// Current status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitus
本綜述探討天然迷幻劑賽洛西賓作為主觀耳鳴新療法的潛力｜賽洛西賓激活5-HT2A受體，促進谷氨酸釋放及腦源性神經營養因子(BDNF)表達，增強大腦關鍵區域的突觸連結｜此機制有助調節耳鳴相關的神經傳導物質失衡，為恢復神經可塑性提供新方向。
// This review explores the potential of psilocybin, a natural psychedelic, as a novel treatment for subjective tinnitus by targeting neural plasticity mechanisms. Psilocybin activates 5-HT2A receptors, increasing glutamate release and BDNF expression, which enhances synaptic connectivity in key brain areas. The study highlights how these effects may synergistically regulate neurotransmitter imbalances involved in tinnitus. Overall, psilocybin could offer a promising new approach by restoring neural plasticity and neurotransmitter balance in tinnitus patients.
Published 2026年6月14日
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