下丘對上丘之興奮性與抑制性投射的層狀分離

// Laminar segregation of excitatory and inhibitory projections from the inferior colliculus to the superior colliculus

本研究利用病毒及逆行標記技術，在基因改造鼠中描繪下丘腦膝狀體（IC）到上丘腦膝狀體（SC）的興奮性與抑制性投射｜發現抑制性投射偏好淺層SC，興奮性投射則主要分布於深層｜抑制性神經元多位於IC的前緣殼區，尤其影響淺層SC，揭示了聽覺訊息可能調控視覺處理的新機制。

// This study mapped excitatory and inhibitory projections from the inferior colliculus (IC) to the superior colliculus (SC) using viral and retrograde tracing in genetically modified mice. It found that inhibitory IC projections preferentially target superficial SC layers, while excitatory projections mainly innervate deeper SC layers. Inhibitory neurons projecting to the SC were more common in rostral IC shell areas, especially for superficial SC layers. These results reveal a distinct IC-SC circuit organization suggesting how auditory inputs might influence visual processing in the SC.

Published 2026年6月13日