嬰兒豬模型中吸入相關肺部病理生理定量灰階分析方法之開發與驗證

// Development and Validation of Quantitative Greyscale Analyses for the Detection of Aspiration-related Lung Pathophysiology in an Infant Pig Model

本研究開發並驗證高速透視影像法，追蹤幼豬吸入異物後肺部變化｜利用鋇液餵食過程中灰階測量，準確檢測肺部液體滲入和數日累積情況｜結果顯示肺部損傷涉及多重因素，與吸入頻率僅有弱相關｜此方法有助未來探討氣道防護與肺健康的關聯。

// This study developed and validated methods to track lung changes after aspiration using high-speed videofluoroscopic recordings in infant pigs feeding on barium milk. Lung greyscale measurements reliably detected liquid infiltration during feeding and accumulation over days, correlating weakly with aspiration frequency. Results suggest lung damage from aspiration involves additional factors beyond penetration scores. These methods enable future research on the relationship between airway protection and lung health in this model.

Published 2026年6月17日