Otology & Neuerotology2026年6月27日

局部及全身性阿魏酸治療對大鼠鼓膜硬化症的保護作用

// Protective Effects of Topical and Systemic Ferulic Acid Treatment on Myringosclerosis in a Rat Model

本研究探討阿魏酸(FA)對大鼠鼓膜受傷後耳膜硬化症形成的影響|局部及全身給藥均顯著降低膜厚度與炎症指標,局部使用效果優於全身給藥|結果顯示阿魏酸具預防術後耳膜硬化症潛力,建議進一步研究驗證。

// This study investigated the effects of ferulic acid (FA) on myringosclerosis formation in rats after tympanic membrane injury. FA was given either topically or systemically, and both methods significantly reduced myringosclerosis indicators such as membrane thickness and inflammation. Topical FA was more effective than systemic administration in reducing tympanic membrane thickness. The results suggest FA could help prevent postoperative myringosclerosis and deserve further research.

#Coumaric Acids#Myringosclerosis#Antioxidants

Published 2026年6月25日

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