耳毒性後大鼠尾部抬舉及空中翻正反射缺損與前庭I型毛細胞喪失相關

// Deficits in tail-lift and air-righting reflexes in rats after ototoxicity associate with loss of vestibular type I hair cells

本研究探討耳毒性化學物質造成的前庭毛細胞損傷，對雌性大鼠抗重力反射的影響｜結果顯示尾舉反射和空中翻轉反射主要依賴第一型毛細胞，且前者關聯於崑狀體與橢圓囊，後者則依賴橢圓囊與球囊｜研究釐清兩種反射的不同前庭感覺來源，強化對前庭功能損傷機制的理解。

// This study investigated how different vestibular hair cell types contribute to anti-gravity reflexes in female rats after graded damage from an ototoxic chemical. They measured loss of type I and II hair cells in specific vestibular regions and corresponding reflex impairments. Findings showed both tail-lift and air-righting reflexes mainly depend on type I hair cells, but each reflex relies on different vestibular organs: tail-lift on crista/utricle and air-righting on utricle/saccule. This clarifies distinct sensory origins underlying these vestibular reflexes.

Published 2026年6月27日