Scientific Reports2026年7月2日

糖尿病肥胖大鼠聽力受損與眼部併發症:疾病進展的橫斷面研究

// Hearing impairment and ocular complications in Zucker diabetic fatty rats: a cross-sectional study across disease progression

本研究評估糖尿病大鼠的眼睛與聽力功能惡化情況|透過眼底血管攝影與聽覺腦幹反應測試,發現早期高頻聽力損失,後續聽力缺陷擴大並加重視網膜損傷|血糖升高與聽力閾值及白內障嚴重度密切相關,顯示慢性糖尿病導致多系統感官功能逐漸衰退。

// This study assessed ocular and auditory dysfunction progression in Zucker diabetic fatty rats with chronic hyperglycemia. Using fundus angiography and auditory brainstem response testing at multiple ages, researchers found early high-frequency hearing loss followed by broader auditory deficits and increased retinal damage over time. Elevated blood glucose strongly correlated with worsening hearing thresholds and cataract severity. The findings demonstrate progressive multisystem sensory impairments linked to sustained diabetes in this animal model.

#Diabetic Retinopathy#Hearing Loss#Diabetes Mellitus, Experimental

Published 2026年7月1日

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