唾液中物質P濃度與嬰幼兒攝食吞嚥攝影中誤吸之關聯性

// Association between Salivary Substance P and Aspiration on Videofluoroscopic Swallow Study in Infants and Toddlers

本研究探討唾液中物質P（SP）濃度與兩歲以下口咽部吞嚥障礙兒童吞嚥吸入風險的關聯｜50名嬰兒唾液檢測顯示，吸入者SP濃度顯著較高｜ROC分析證實SP對吞嚥吸入具高靈敏度與特異性，尤其採樣時間距離影像檢查一個月內｜結果顯示唾液SP可能成為早期預測兒童吞嚥吸入風險的重要生物標記。

// This study examined whether salivary substance P (SP) levels correlate with aspiration detected by videofluoroscopic swallow study (VFSS) in children under 2 years old with oropharyngeal dysphagia. Using ELISA to measure SP in saliva samples from 50 infants, researchers found significantly higher SP concentrations in those with aspiration. ROC analysis showed high sensitivity and specificity of SP levels in predicting aspiration, especially when saliva was collected within one month of VFSS. The findings suggest salivary SP could be a useful early biomarker for aspiration risk in young children.

Published 2026年7月1日