標準與地塞米松釋放電極陣列之接觸阻抗、極化阻抗及巢狀雙極阻抗之時空動態比較

// Comparative spatiotemporal dynamics of access resistance, polarization impedance, and nested bipolar impedance in standard and dexamethasone-eluting electrode arrays

本研究比較接受人工耳蝸植入者使用標準與地塞米松釋放電極陣列（Dex-EAs）之阻抗測量｜發現完全位於耳蝸內的巢狀雙極阻抗對局部組織變化更敏感，Dex-EAs組12個月阻抗較低且穩定，顯示炎症與纖維化減少｜結果支持巢狀雙極阻抗作為監測耳蝸內環境變化的精確生物標記。

// This study compared impedance measurements in cochlear implant recipients using standard versus dexamethasone-eluting electrode arrays (Dex-EAs) to assess inflammatory responses and tissue changes. Nested bipolar impedance, recorded entirely intracochlearly, was more sensitive to local tissue alterations than access resistance (Ra) or polarization impedance (Zp). Dex-EAs showed consistently lower and more stable impedance over 12 months, indicating reduced inflammation and fibrosis. The findings support nested bipolar impedance as a precise biomarker for monitoring intracochlear environment changes.

Published 2026年7月16日