Hearing Research2026年7月27日
COMPARATIVE

近場記錄揭示遠場測量周邊前庭神經活動的限制:對實驗控制的影響

// Near-field recordings expose the limits of far-field measures of peripheral vestibular nerve activity: implications for experimental controls

本研究比較近場(NF)面神經管與遠場(FF)頭皮記錄的耳石器短潛伏期誘發電位(VsEPs)|NF記錄在耳石神經附近,振幅更大、訊噪比更高,能更準確反映缺氧及神經阻斷下的神經功能損失|FF記錄則低估神經異常且含非神經訊號,顯示NF方法對評估前庭神經活動更敏感有效。

// This study compares near-field (NF) facial nerve canal and far-field (FF) scalp recordings of vestibular short-latency evoked potentials (VsEPs) in guinea pigs. NF recordings near the vestibular nerve showed much larger amplitudes and higher signal-to-noise ratios than FF scalp responses. NF VsEPs more accurately reflected vestibular nerve function loss under hypoxia and neural blockade, while FF responses underestimated dysfunction and included non-neural signals. The findings highlight NF facial nerve canal recording as a more sensitive method for assessing vestibular nerve activity.

#Vestibular Nerve

Published 2026年7月26日

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