兒童急性結核性腦膜炎耳病理學病例系列

// Otopathology of Pediatric Acute Tuberculous Meningitis-Case Series

本研究調查結核性腦膜炎（TBM）嬰兒耳內損傷，探討其與感音神經性聽損的關聯｜分析三例顳骨，發現耳蝸纖維化、考蒂器萎縮及神經細胞減少，且聽道有膿液存在｜確認感染自腦部經耳蝸水管、內淋巴囊及羅森塔耳道擴散，揭示TBM引起聽損的內耳損傷機制。

// This study examined inner ear damage in infants who died from tuberculous meningitis (TBM) to understand its role in sensorineural hearing loss. Researchers analyzed three temporal bones, finding acute injury like cochlear fibrosis, organ of Corti atrophy, and neuronal loss with pus in the auditory canal. They identified the cochlear aqueduct, endolymphatic sac/duct, and Rosenthal's canal as pathways through which infection spreads from the brain to the inner ear. These findings clarify how TBM causes hearing loss by damaging inner ear structures.

Published 2026年7月30日