鐮刀型紅血球症青少年期紋狀血管帶、螺旋神經節及前庭神經節細胞之定量顳骨分析

// Quantitative Temporal Bone Analysis of Stria Vascularis, Spiral Ganglion, and Vestibular Ganglion Cells in Sickle Cell Disease at Young Ages

研究利用深度學習分析顳骨標本，對比年輕鐮刀型細胞疾病（SCD）患者與對照組的內耳結構｜血管條面積、螺旋神經節細胞及前庭神經節神經元數量無顯著差異，雙方聽力閾值均正常｜結果顯示，SCD患者內耳退化可能於聽力損失發生後才開始發展，具預防與早期診斷意義。

// This study compared inner ear structures in young sickle cell disease (SCD) patients and controls using deep learning on temporal bone samples. Measurements of stria vascularis area, spiral ganglion cell counts, and vestibular ganglion neuron counts showed no significant differences between groups, despite some qualitative atrophy signs in SCD cases. Both groups had normal hearing thresholds. Findings suggest that inner ear degeneration in SCD may develop after hearing loss begins.

Published 2026年8月3日