Audiology and Neurotology2026年8月7日
REVIEW

鼓內類固醇療程預防順鉑引起聽力損失:系統性文獻回顧

// Intratympanic Steroid Regimen For Prevention Of Cisplatin-Induced Hearing Loss: A Systematic Review

本綜述評估了2004至2023年間四項隨機對照試驗,探討鼓室內類固醇治療(ITD)預防順鉑引起的聽力損失|研究結果不一致,且存在偏差風險,未提供ITD具保護耳毒性的強力證據|因方法差異大,結論有限,亟需更嚴謹標準化的臨床試驗以釐清療效。

// This review evaluated intratympanic steroid administration (ITD) to prevent cisplatin-induced hearing loss by analyzing four randomized controlled trials from 2004 to 2023. The studies showed inconsistent results and had risks of bias, with no strong evidence supporting ITD's protective effect against ototoxicity. Methodological differences across studies limited conclusions. More rigorous, standardized trials are needed to clarify ITD's efficacy in this setting.

Published 2026年8月5日

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