Otology & Neuerotology2026年8月12日

耳廓迷走神經刺激對麻醉大鼠模型心血管及自律神經影響

// Cardiovascular and Autonomic Effects of Auricular Vagus Nerve Stimulation in an Anesthetized Rat Model

本研究探討外耳不同區域電刺激對麻醉大鼠心血管功能的影響|發現藍芽刺激耳甲部位能劑量依賴性改變平均動脈壓,透過副交感與交感神經共同調控|雙側迷走神經切斷部分減弱反應,完全自律神經阻斷則完全消除,顯示耳迷走神經刺激能雙向調節心血管活動。

// This study investigated how electrical stimulation of different regions of the external ear affects cardiovascular function in anesthetized rats. Using bipolar transcutaneous stimulation and autonomic blockades, the researchers found that stimulation at the concha induced significant, dose-dependent changes in mean arterial pressure mediated by both parasympathetic and sympathetic nervous pathways. Bilateral vagotomy reduced but did not eliminate responses, while complete autonomic blockade abolished them, showing that aVNS modulates cardiovascular activity via both autonomic branches.

#Vagus Nerve Stimulation#Autonomic Nervous System#Vagus Nerve

Published 2026年8月10日

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