改善頭頸癌存活者慢性放射線相關性吞嚥困難之口腔功能攝入 — 多中心隨機對照 HIT-CRAD 試驗

// Improving Functional Oral Intake in Head and Neck Cancer Survivors with Chronic Radiation-Associated Dysphagia - The Multicenter Randomized Controlled HIT-CRAD Trial

本隨機對照試驗比較居家肌力訓練、肌力與技巧結合訓練，以及結合真實或假性高解析度經顱直流刺激（HD-tDCS）對頭頸癌輻射後慢性吞嚥困難患者的效果｜8週後所有組別的口服攝取量、吞嚥功能與肌力均有提升，其中結合訓練組口服攝取改善最顯著｜增加HD-tDCS未見額外益處，顯示結合肌力與技巧訓練為改善此類患者吞嚥困難的最佳方案。

// This randomized controlled trial compared home-based strength training, combined strength-skill training, and combined training with real or sham HD-tDCS in head and neck cancer patients with chronic radiation-associated dysphagia. All groups improved in oral intake, swallowing function, and muscle strength after 8 weeks, but combined strength and skill training led to significantly better oral intake outcomes than strength training alone. The addition of HD-tDCS showed no extra benefit. Thus, combined strength and skill training is the most effective treatment for improving dysphagia in these patients.

Published 2026年8月13日