失敗指數作為MED-EL人工耳蝸使用者神經健康狀態標記：一項回顧性分析

// The Failure Index as Marker of the Neural Health Profile in MED-EL CI Users: A Retrospective Analysis

本研究採用由電刺激誘發複合神經動作電位（eCAP）衍生的失效指數（FI）評估人工耳蝸使用者的耳蝸健康｜278個耳朵的回溯分析顯示，FI術後穩定且隨年齡增加，能反映耳蝸內神經變化，與電極位置無關｜FI與語音理解能力相關性高，特別是在後語聾患者，具指示螺旋神經節神經元存活狀況及神經健康的應用價值。

// This study translated the Failure Index (FI), a marker derived from electrically-evoked compound action potentials (eCAP), to evaluate cochlear health in human cochlear implant users. Retrospective analysis of 278 ears showed FI was stable postoperatively, increased with age, and reflected neural health variations along the cochlea, independent of electrode placement. FI correlated better with speech perception than other eCAP measures, especially in postlingual deafness. The findings suggest FI can effectively identify areas of reduced spiral ganglion neuron survival and help assess neural health in implanted ears.

Published 2026年8月20日