// Normative Ranges for Auditory Brainstem Response Wave I Amplitude: A Potential Diagnostic Indicator of Cochlear Deafferentation
本研究建立了聽覺腦幹反應（ABR）波形I振幅的正常範圍，用以檢測正常聽力者的耳蝸突觸病變｜以低風險族群作為標準，並比較具聽覺問題的高風險退伍軍人｜結果顯示性別特異的ABR波形I振幅能有效區分高風險族群，無需調整外毛細胞功能異常，提升臨床診斷準確性。
// This study aimed to establish normative ranges for auditory brainstem response (ABR) Wave I amplitude to detect cochlear synaptopathy in individuals with normal hearing. Researchers generated ABR normative data from a low-risk population and compared it with a high-risk group of military Veterans having auditory complaints. They found that sex-specific ABR Wave I amplitude ranges effectively distinguish high-risk individuals with cochlear deafferentation without needing adjustment for outer hair cell dysfunction. These findings suggest clinicians can use sex-specific ABR norms to identify cochlear synaptopathy in patients with normal audiograms.
Published 2026年8月24日
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