// Tinnitus and decreased sound tolerance in military Veterans: Relationship with cochlear deafferentation
退伍軍人聽力圖正常，仍顯示耳蝸去神經化與高頻外毛細胞(OHC)微損｜ABR wave I、EFR、高頻DPOAE下降，ABR V/I比升高；MEMR在DST組平均下降但耳鳴組不穩定｜意涵：須重視隱性聽損與改進診斷標記，中央增益或促成耳鳴與聲音耐受下降
// The study tested whether military Veterans with normal audiograms but constant tinnitus and/or decreased sound tolerance (DST) show physiological signs of cochlear deafferentation compared with young, low-noise-exposure controls. Researchers measured ABR wave I amplitude, envelope following response (EFR) magnitude, wideband middle ear muscle reflex (MEMR) magnitude, and high-frequency DPOAEs. Veterans had reduced ABR wave I amplitudes, smaller EFRs, and diminished high-frequency DPOAEs (with average MEMR reductions in the DST group but inconsistent MEMR findings in tinnitus cases) and often elevated ABR V/I ratios. The results suggest cochlear deafferentation and subclinical high-frequency outer hair cell dysfunction in these Veterans, MEMR is an unreliable deafferentation marker, and increased central gain may contribute to tinnitus and DST.
Published 2026年9月15日
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