肥胖與兒童腺樣體及扁桃體切除術後呼吸併發症：高風險併存症效應修飾之全國性分析

// Obesity and respiratory complications after pediatric adenotonsillectomy: A national analysis of effect modification by high-risk comorbidities

研究顯示肥胖提高兒童門診腺樣體/扁桃體手術圍手術期呼吸不良事件（PRAEs），調整後aOR 1.62（95% CI 1.42–1.86）｜肥胖合併氣喘時合併比值2.07，低於預期2.89，顯示風險重疊，建議對有氣喘肥胖兒童延長術後觀察。

// The study tested whether obesity increases perioperative respiratory adverse events (PRAEs) in children having ambulatory adenotonsillectomy/tonsillectomy/adenoidectomy and whether high-risk comorbidities change that risk. Researchers performed a retrospective cross-sectional analysis of the HCUP Nationwide Ambulatory Surgery Sample (2016–2022) for patients <18, identifying obesity and PRAEs by ICD‑10 codes and using survey-weighted logistic regression adjusted for demographics, comorbidities, payer, income, hospital factors, and year. Obesity independently raised PRAE risk (fully adjusted aOR 1.62, 95% CI 1.42–1.86). A sub-multiplicative interaction with asthma (combined OR 2.07 < expected 2.89) suggests overlapping risk pathways and supports a lower threshold for extended postoperative observation in obese children with asthma.

Published 2026年9月16日