International Journal of Pediatric Otorhinolaryngology2026年9月21日
REVIEW

產前母體壓力與子代過敏性鼻炎風險:系統性回顧與薈萃分析

// Prenatal maternal stress and the risk of allergic rhinitis in offspring: A systematic review and meta-analysis

薈萃9項研究n=40,630顯示孕期壓力提高兒童過敏性鼻炎風險|OR1.69(95%CI1.51–1.86);按類型:焦慮OR1.42、憂鬱OR1.61、生活壓力OR1.74|孕期壓力越高、特定壓力更甚,兒童罹患率增加,應加強產前心理支持。

// This meta-analysis assessed whether prenatal maternal stress raises the risk of allergic rhinitis in children by pooling nine studies (40,630 participants) from major databases up to May 20, 2026 and calculating pooled odds ratios. Overall prenatal stress was linked to higher offspring AR risk (OR 1.69, 95% CI 1.51–1.86), with a gradient by stress type: anxiety (OR 1.42), depression (OR 1.61), and stressful life events (OR 1.74). The authors conclude that maternal stress during pregnancy increases the likelihood of childhood allergic rhinitis, with more severe or specific stressors associated with greater risk.

Published 2026年9月19日

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